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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice

Fig. 6

IL-1β, TNFα, 5-HT2A receptor and SERT mRNA expression in the brain structures of animals challenged with chronic stress, LPS or a combination of both. mRNA levels of a IL-1β, b TNFα, c 5-HT2A and d SERT were measured by qPCR in the pre-frontal cortex, striatum, hippocampus and raphe of animals after either 10 days of chronic stress, an acute LPS challenge (0.1 mg/kg) or a combination of both. Values are expressed as relative-fold expression normalized to housekeeping gene GAPDH and to control values within each region. Data are mean ± SEM; n = 5 in each group; *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001 compared to control animals

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