Fig. 3

Impaired antibody response to influenza in chronic SCI mice. a Influenza virus-specific antibody response was assessed by ELISA using H3N2 virus-coated plates and diluted sera from chronic SCI and CT mice 5 or 7 days post-infection. Bar graphs represent the mean ± SEM, 5 mice/group. Data was normalized after subtracting the values from uninfected mice from both the uninjured and injured groups at day 0 prior to infection. b Virus-specific IgA response was measured in the BAL of infected mice on day 5 and day 7. Mean ± SEM, 5 mice/group. c The ability of the antibodies to neutralize the virus was tested using serial dilutions of the serum from uninjured CT and SCI mice