Fig. 5
Myelin alteration in the spinal cord and corpus callosum of NMO-rat. a Myelin alteration detected by myelin basic protein (MBP) immunostaining in the spinal cord (gray (GM) and white matter (WM)) and corpus callosum (CC) of the NMO-rats compared to the Control-rat (D7, rats infused with IgGAQP4+1,2 and IgGControl2 as example). b MBP decreased expression in the spinal cord and corpus callosum of the NMO-rats (n = 4) compared to the Control-rats (n = 5), as shown by evaluation of fluorescence intensity (p < 0.05, ANOVA). Scale bars = 20 μm