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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Early life overfeeding impairs spatial memory performance by reducing microglial sensitivity to learning

Fig. 7

Numbers and density of ionized calcium-binding adapter molecule-1 (Iba-1)-positive cells at postnatal day 70 in rats raised in control (CL) and small (SL) litters under basal conditions and 24 h after the last radial arm maze (RAM) training session. a, b, and e CA1. c, d, and f CA3. g, h Dentate gyrus hilus. i, j Molecular region. k, l DG sub-granular (SG)/granular region. m Scatterplots of correlations between SL, but not CL, Iba-1 density and RAM reference errors bin 5 in the molecular region of the DG. n Scatterplots showing lack of correlation between CL and SL body weight and RAM reference errors bin 5. o, p Numbers and density of Iba-1-positive cells in the retrosplenial dysgranular cortex (RSD). qs Retrosplenial granular cortex (RSGc). Data are mean + SEM. N = 6–12 per group. *p < 0.05. e, f, and s Representative photomicrographs of Iba-1. Scale bars = 100 μm

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