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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Inhibition of myeloperoxidase oxidant production by N-acetyl lysyltyrosylcysteine amide reduces brain damage in a murine model of stroke

Fig. 1

KYC significantly reduced neurological deficit and brain infarct size in mice subjected to MCAO. a Effects of KYC on neurological severity scores during 7 days after MCAO. Top panel: Experimental scheme; KYC (10 mg/kg/day) or PBS via i.p. was administrated starting 1 h after reperfusion. Bottom panel: Neurological severity scores of mice after MCAO (*p < 0.05, KYC vs. PBS group at same time interval, nonparametric Mann-Whitney test); b Effect of KYC on infarct size in mice 3 days after MCAO. Images of brain coronal sections (20-μm thick, 1-mm interval from rostral to caudal) by cresyl violet stain were shown; c Infarct volume (*p < 0.05, KYC vs. PBS group, n = 5/group, t test)

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