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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Inhibition of myeloperoxidase oxidant production by N-acetyl lysyltyrosylcysteine amide reduces brain damage in a murine model of stroke

Fig. 6

Effects of KYC on NO2Tyr and 4-HNE expression in the brain of mice 3 days after MCAO. MCAO mice were prepared as described in Fig. 2. a Images of NO2Tyr immunostaining in the cortex ischemic core areas; b Images of colocalization of MPO and NO2Tyr in brain cortex ischemic core; red: NO2Tyr, green: MPO, and yellow: NO2Tyr + MPO, as arrows indicated; c 4-HNE immunostaining in the cortex ischemic core areas; d Images of colocalization of 4-HNE and MPO in brain cortex ischemic core (red: 4-HNE, green: MPO, and yellow: 4-HNE + MPO, as arrows indicated). All images are the representative images of five repeat samples. e Counts of NO2Tyr positive cells (n = 5, * p < 0.05, KYC vs. PBS group, t test). f Counts of 4-HNE positive cells (n = 5, * p < 0.05, KYC vs. PBS group, t test)

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