Fig. 4From: Cryopreserved vitamin D3-tolerogenic dendritic cells pulsed with autoantigens as a potential therapy for multiple sclerosis patientsTreatment with frozen tolDC-MOG (f-tolDC-MOG) shows a long-term beneficial effect. Clinical follow-up of mice treated with 1 × 106 viable f-tolDC-MOG (n = 15), unpulsed f-tolDC (n = 14) or PBS (vehicle, n = 15) on days +14 pi, +18 pi, +22 pi, +31 pi, +40 pi, +49 pi and +67 pi. Arrows indicate days of treatment administration (a). Error bars correspond to SEM. Representation of individual clinical score of the initial day of treatment (day 14 pi) and the corresponding mean clinical score during the treatment period (from 15 pi to 74 pi) from mice treated with f-tolDC-MOG (n = 15) (b), f-tolDC (n = 14) (c) or PBS (vehicle, n = 15) (d). The mean clinical score during the treatment for each mouse was calculated as the sum of daily scores from day 15 pi to 74 pi divided by 60 (number of follow-up days after treatment)Back to article page