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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Intraperitoneally administered IgG from patients with amyotrophic lateral sclerosis or from an immune-mediated goat model increase the levels of TNF-α, IL-6, and IL-10 in the spinal cord and serum of mice

Fig. 4

The levels of IL-10 in the spinal cord and serum of the inoculated mice. Upper. The levels of IL-10 in the spinal cord of the mice in group 0 and control group were almost the same. The spinal cord of the mice inoculated with the IgG from the ALS patients (ALS group) or from the immunized goats with EAGMD (goat group) contained highly increased levels of IL-10. Lower. IL-10 was not detected in the serum of the mice in group 0 or control group. The serum of the animals in the ALS group and even more so in the goat group contained significantly higher levels of IL-10

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