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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Activated brain mast cells contribute to postoperative cognitive dysfunction by evoking microglia activation and neuronal apoptosis

Fig. 2

Cromolyn inhibited microglia activation in the hippocampus induced by the tibial surgery. a Immunostaining was used to detect Iba1 in area CA1 of the hippocampus, markers for microglia. Scale bar 50 μm. b Quantification of Iba1-positive cells in area CA1 of the hippocampus. c–e Expression levels of M1 phenotype markers (CD86, CD32, and IL-1β). f Expression levels of CD206, markers for M2a phenotype. g Expression levels of SOCS3, markers for M2b phenotype. * P < 0.05, ** P < 0.01 vs. control group. # P < 0.05, ## P < 0.01 vs. surgery group. Data are presented as the mean ± SD (n = 6)

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