Fig. 6
From: STIMs and Orai1 regulate cytokine production in spinal astrocytes
Depletion of Ca2+ store induces cytokine production in spinal astrocytes. a TG-induced TNF-α production. b TG-induced IL-6 production. c CPA-induced TNF-α and IL-6 production (n = 6–8). d Effects of YM-58483 (YM, 3 μM) and GdCl3 (Gd3+, 0.3 µM) on TG-induced cytokine production and reduction of cell viability (n = 6–7). e Effects of knockdown STIM1 or Orai1 on TG-induced cytokine production and reduction of cell viability (n = 6). Values represent mean ± SEM, *P < 0.05, compared with control by Student’s t test or the one-way ANOVA