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Table 2 List of transcripts which expression is upregulated by MOG35-55 stimulation and not affected by CBD

From: Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells

Symbol

Gene name

Accession number

MOG alone [fold]$

MOG+CBD [fold]$

CBD alone [fold]$

Cytokines

 Csf2

Colony stimulating factor 2

NM_009969.2

77.0

67.1

1.1

 Tnf

Tumor necrosis factor alpha

NM_013693.1

15.3

13.8

1.1

 Ifng

Interferon gamma

NM_008337.1

10.8

9.5

0.8

Chemokines

 Ccl3

Chemokine (C-C motif) ligand 3

NM_011337.1

54.1

48.6

0.9

 Ccl4

Chemokine (C-C motif) ligand 4

NM_013652.1

40.2

37.3

0.9

 Cxcl10

Chemokine (C-X-C motif) ligand 10

NM_021274.1

9.0

9.8

0.9

Glycoproteins

 Sema7a

Semaphorin 7A (GPI membrane anchor)

NM_011352.2

4.6

4.3

0.8

Transcription factors

 Egr2

Early growth response 2

NM_010118.1

20.1

18.9

1.3

 Egr1

Early growth response 1

NM_007913.2

10.7

11.7

1.5

 Tbx21

T-box 21

NM_019507.1

2.2

2.5

0.9

Signaling elements

 Ndrg1

N-myc downstream regulated 1

NM_010884.1

6.2

6.7

2.5

 Ifit3

Interferon-induced protein with tetratricopeptide repeats 3

NM_010501.1

5.6

5.9

0.9

  1. $The results are presented as fold change vs control (without MOG35-55 or CBD). Numbers in italics indicate a significant effect of CBD alone (p < 0.005)