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Table 5 IPA-identified “top canonical pathways” enriched by CBD treatment in stimulated TMOG cells

From: Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells

Canonical pathways Annotated genes p value
IL-10 signaling Hmox1, Il1b, Jun, Socs3 0.0039
IL-6 signaling Il1b, Jun, Socs3, Srf, Vegfa 0.0042
cAMP-mediated signaling Crem, Fpr2, Gnal, Grm6, Hrh3 0.024
IGF-1 signaling Igfbp4, Jun, Socs3, Srf 0.015
Fcγ receptor mediated phagocytosis in macrophages and monocytes Appc3, Hck, Hmox1, Vav3 0.012
Superpathway of cholesterol biosynthesis Fdps, Sqle 0.016
T helper cell differentiation CD40, Ifbgr1, Il21 0.042