Table 1 Characteristics of the rhesus macaques
From: Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself
Animal ID | Gender | Age (year) | Weight (kg) | Immunizations (d) | EAE score ≥2 (d) | Euthanasia (d) | EAE score at euthanasia | Ref |
|---|---|---|---|---|---|---|---|---|
Rhesus EAE | ||||||||
R05045 | M | 8 | 10.7 | rhMOG/CFA (0) | 12 | 12 | 5 | [54] |
R06052 | M | 7 | 7.7 | rhMOG/CFA (0) | 13 | 13 | 5 | [54] |
R07035 | M | 6 | 10.0 | rhMOG/CFA (0) | 16 | 16 | 5 | [54] |
R06088 | M | 7 | 11.4 | rhMOG/CFA (0) | 17 | 18 | 5 | [54] |
R08043 | M | 5 | 8.1 | rhMOG/CFA (0) | 21 | 21 | 5 | [54] |
R06030 | M | 7 | 12.2 | rhMOG/CFA (0) | 26 | 27 | 5 | [54] |
Ri0106111 | M | 9 | 12.5 | rhMOG/IFA (0, 28) | 40 | 41 | 5 | [53] |
Ri970621 | M | 9 | 8.3 | rhMOG/IFA (0, 28) | 46 | 48 | 2.5 | [53] |
Controls | ||||||||
R8765 | F | 11 | 9.5 | – | – | – | – | |
R02095 | M | 5 | 11.3 | – | – | – | – | |
R9222 | F | 17 | 9.3 | – | – | – | – | |
R97058 | M | 12 | 11.5 | rhMOG/CFA (0) | – | 22 | 0 | [52] |
R01097 | M | 9 | 13.9 | rhMOG/CFA (0) | – | 18 | 0 | [52] |
Ri9604157 | M | 14 | 8.2 | rhMOG/IFA (0, 28, 56, 84) | – | 111 | 0 | [53] |
Ri9805013 | M | 12 | 9.3 | rhMOG/IFA (0, 28) | – | 28 | 0 | [53] |