Skip to main content

Table 1 Summary of multiple sclerosis and control groups used for quantitative analysis

From: Complement is activated in progressive multiple sclerosis cortical grey matter lesions

Cohort

Status (n)

Gender

Age at death

Disease duration

PMD

Multiple sclerosis

18 SPMS

9M:13F

50 years (38–66)

25 years (10–39)

17 h (9–26)

4 PPMS

Inflammatory Ctrls

4 viral encephalitis

6M:2F

37 years (17–65)

n/a

36 h (24–72)

4 ischaemia

Non-neurological Ctrls

15 controls

9M:6F

67 years (35–88)

n/a

24 h (5–48)

  1. Inflammatory controls are non-MS neurological controls characterised by neuroinflammation and gliosis. Group values showed as median (data range). See (Additional file 1: Table S1) for individual case details including cause of death, disease activity at death and sampled blocks
  2. Ctrls controls, disease duration determined retrospectively from time of first symptom onset to death, F female, M male, PMD post-mortem delay, PPMS primary progressive MS, SPMS secondary progressive MS, n/a not applicable