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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Phenotypic clustering: a novel method for microglial morphology analysis

Fig. 3

Characteristics of the amoeboid population and their inter-region variability. Bar charts represent the characteristics of the amoeboid cell morphology (characterized by a CI = 1, without nodes) and the distribution within the four explored regions: hippocampus (H), frontal cortex (FC), striatum (S) and cerebellum (C) in the two different conditions, the control (left column) and the LPS (right column). a Parameters to characterize the amoeboid cells morphology: the cell body area and the cytoplasm area defined as the cell body area associated with the cytoplasmic area of the primary ramifications in μm2. b Parameters to characterize the amoeboid cell distribution: density calculated by dividing the number of microglial cells selected by the scanned tissue area (3.03 mm2) and frequency as the ratio between the number of amoeboid cells and the total number of microglial cells analysed. Data shown are means ± SD per condition (n = 7, n = 6 for control and LPS, respectively); we used ANOVA Kruskal-Wallis test. **p < 0.01, ***p < 0.001

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