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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Rice bran derivatives alleviate microglia activation: possible involvement of MAPK pathway

Fig. 2

RBE inhibits the release of 8-isoprostane (8-iso-PGF2α) in LPS-activated microglia. Microglia cells were pre-treated with RBE (10–300 μg/ml) for 24 h; thereafter, cells were incubated with or without LPS (10 ng/ml) for the next 24 h. At the end of incubation, cell supernatants were collected and release of 8-iso-PGF2α was measured by EIA. Statistical analysis was carried out by using one-way ANOVA with post hoc Student-Newman-Keuls test (multiple comparisons). Results are expressed as means ± SEM of three independent experiments. * p < 0.05 compared with LPS (10 ng/ml)-activated cells

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