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Table 1 Somatic and brain growth in C57BL6/J and BTBR mice prenatally exposed to CPF

From: Prenatal exposure to the organophosphate insecticide chlorpyrifos enhances brain oxidative stress and prostaglandin E2 synthesis in a mouse model of idiopathic autism

  

C57BL6/J

BTBR

C57BL6/J

BTBR

  

Body weight (g)

Brain weight (mg)

PND 1

Vehicle

1.75 ± 0.052

1.61 ± 0.084

75 ± 5

66 ± 3

 

CPF

1.68 ± 0.097

1.67 ± 0.120

70 ± 9

63 ± 2

PND 21

Vehicle

nt

14.30 ± 0.88

nt

157 ± 6

 

CPF

nt

11.07 ± 1.05*

nt

149 ± 6

PND 70

Vehicle

23.92 ± 1.76

30.71 ± 1.62

297 ± 18

327 ± 12

 

CPF

24.68 ± 1.69

29.4 ± 1.33

307 ± 8

317 ± 12

  1. Data are means ± SEM (n = 10–12 for BTBR and n = 6–7 for C57BL6/J); *p < 0.05 versus vehicle-exposed BTBR mice at same PND
  2. nt not tested
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Journal of Neuroinflammation

ISSN: 1742-2094