Fig. 1

DcR3 treatment improved the hind limb functional recovery in SCI rats. Rats were contused at the T9 level of the spinal cord using the NYU impactor (10-g rod dropped from a height of 50 mm), followed by injection of 15 μg of DcR3.Fc in 5 μl of normal saline or 5 μl of normal saline only (control) at the injury epicenter. The functional recovery of the spinal cords was evaluated weekly using the BBB test. DcR3.Fc treatment yielded higher scores from the second week until the animals were euthanized (sixth week). (*p < 0.05, **p < 0.01, DcR3.Fc, N = 7; control, N = 10). The results are presented as means ± SEM