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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: The immunomodulator decoy receptor 3 improves locomotor functional recovery after spinal cord injury

Fig. 5

DcR3 treatment attenuates M1 macrophages in the lesion site of injured rat spinal cords. Expression of IL-1β at the lesion sites of DcR3.Fc-treated and control SCI rats. a Detection of IL-1β/OX42-positive cells in two groups by immunofluorescence staining (IL-1β, red; OX42, green; scale bar: 100 μm). b Quantification as a percentage of the IL-1β/OX42-positive area from the two groups in the lesion sites. The results showed that DcR3Fc-treated group had a lower percentage of IL-1β/OX42-positive area in the lesion site (left, *p < 0.05, N = 3). The results are presented as means ± SEM

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