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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: C-C motif chemokine ligand 20 regulates neuroinflammation following spinal cord injury via Th17 cell recruitment

Fig. 9

The postulated inflammatory positive feedback in neuroinflammation following SCI. IL-17 interacts with the corresponding receptors on the surfaces of certain target cells and induces the production of IL-6, IL-1β, TNF-α, and CCL20. Subsequently, IL-6, IL-1β, and TNF-α further stimulate IL-17 expression and differentiation of Th17 cells. The black solid line represents what we have proven in the present study. The purple dotted line represents what we have speculated from other studies

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Journal of Neuroinflammation

ISSN: 1742-2094