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Table 1 Extracellular loop mutations

From: Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders

Loops

Name

WT sequence

Mutated sequence

A

AQP4-delA3

66LPVD69

66AAAA69

A

AQP4-mycA

59WGGT62

59WG-myc-GT62

C

AQP4-N153Q

150VHGNLT155

150VHGQLT155

C

AQP4-mycC

140SVVG143

140SV-myc-VG143

E

AQP4-H230G

228ENHW231

228ENGW231

E

AQP4-mycE

226NWEN229

226myc-NWEN229

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Journal of Neuroinflammation

ISSN: 1742-2094