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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Gas1 up-regulation is inducible and contributes to cell apoptosis in reactive astrocytes in the substantia nigra of LPS and MPTP models

Fig. 1

Induction of Gas1 expression and cleaved caspase-3 (CC-3) in the nigral astrocytes of LPS rat model. a Double labeling shows Gas1/GFAP-positive astrocytes in the substantia nigra of control and LPS group and magnified in inserts. b Immunoblots of Gas1 and CC-3 in the ventral midbrains of control and LPS-2-, 3-, and 4-week groups. c Comparison of Gas1 and CC-3 levels among above groups (density in ratios of interested groups compared with control). d GFAP/CC-3 double labeling in the nigra of control and LPS group. e Comparison of GFAP/CC-3-positive astrocytes between control and LPS group. ANOVA, *P < 0.05, **P < 0.01 vs control (mean ± S.E.M., n = 3)

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