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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia

Fig. 3

Top IPA-based canonical pathway analyses at 4 h after LPS stimulation in BV2 cell lines and PM. a, b Ingenuity® Bioinformatics pathway analysis revealed that highly canonical pathways were differentially expressed in BV2 cell lines and PM cells after LPS stimulation. The canonical pathways included in this analysis are shown along the y-axis of the bar chart. The x-axis indicates the statistical significance. Calculated using the right-tailed Fisher exact test, the P value indicates which biologic annotations are significantly associated with the input molecules relative to all functionally characterized mammalian molecules and the yellow threshold line represents the default significance

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Journal of Neuroinflammation

ISSN: 1742-2094