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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease

Fig. 3

Fluoro-Jade C staining of the ventral spinocerebellar tract of the brainstem. a Fixed, frozen 30-μm brainstem (dorsal medulla) sections were stained with Fluoro-Jade C. Low-powered images show staining of the ventral spinocerebellar tract (VSCT) with no staining of the superior cerebellar peduncle (SCP). High-powered images are taken from the area of the VSCT labeled with arrows. b. Quantification of Fluoro-Jade C intensity was performed on 10 images from three animals per experimental group (30 images per condition). The mean densitometric fluorescence intensity was calculated using ImageJ software, and groups were compared using the student’s t test. *p ≤ 0.05; **p ≤ 0.01. CBL cerebellum, 4V 4th ventricle

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Journal of Neuroinflammation

ISSN: 1742-2094