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Table 2 Differential expression of miRNAs between untreated NMO patients and HCs

From: Circulating microRNAs as biomarkers for rituximab therapy, in neuromyelitis optica (NMO)

Upregulated miRNAs Downregulated miRNAs
miRNAs NMO vs HCs Fold change p value miRNAs NMO vs HCs Fold change p value
hsa-miR-760 (#^) 10.6 0.00021 hsa-miR-7 0.19 0.00034
hsa-miR-423-3p (#) 1.6 0.0008 hsa-miR-140 0.4 0.00042
hsa-miR-660 (#) 6.1 0.00118 hsa-miR-22 0.57 0.00108
hsa-miR-135a (#^) 5.3 0.00202 hsa-miR-143 0.11 0.00109
hsa-miR-135b (#^) 8 0.00329 hsa-miR-150 0.35 0.00126
hsa-miR-1180 2.8 0.00562 hsa-let-7b 0.51 0.00221
hsa-miR-203 (#) 6.5 0.00862 hsa-miR-2110 0.14 0.00541
hsa-miR-18a 1.7 0.01101 hsa-miR-29a 0.28 0.00612
hsa-miR-20b 1.9 0.01591 hsa-miR-342 0.24 0.0103
hsa-miR-100 (#) 2.8 0.02 hsa-miR-10b 0.21 0.01041
hsa-miR-205 6.5 0.0228 hsa-miR-1227 0.12 0.01501
hsa-miR-134 (#^) 4.6 0.02493 hsa-miR-21 0.54 0.01947
hsa-miR-542 6.5 0.03172 hsa-miR-133b 0.16 0.01964
hsa-miR-125b (#^) 1.7 0.0413 hsa-miR-532-5p 0.33 0.02214
hsa-miR-551b 5.7 0.04761 hsa-miR-30e 0.47 0.03266
hsa-miR-454 2.1 0.04839 hsa-miR-133a 0.24 0.03284
hsa-miR-138 (#^) 3.5 0.04892 hsa-miR-139 0.23 0.04032
    hsa-miR-124 0.33 0.0424
    hsa-miR-130b 0.44 0.04353
    hsa-miR-378 0.48 0.0439
    hsa-miR-215 0.28 0.04642
    hsa-miR-411 0.19 0.04853
    hsa-miR-30a 0.32 0.04876
    hsa-miR-27a 0.46 0.04906
    hsa-miR-107 0.7 0.05042
  1. miRNAs with increased expression in NMO patients that were normalized following rituximab therapy are indicated by (#); brain-specific/enriched miRNAs are marked with (^)