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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Aqueous extract from the Withania somnifera leaves as a potential anti-neuroinflammatory agent: a mechanistic study

Fig. 4

ASH-WEX- and FIV-mediated prevention of oxidative stress induced due to neuroinflammation in primary microglia. A Represents the confocal images of the (a) CellROX staining, (b) Mitotracker staining, and (c) HSP 70 immunostaining of the LPS-activated primary microglia with or without pretreatment with ASH-WEX and FIV illustrating the decreased levels of the reactive oxygen species and prevention of the mitochondrial turbulences induced due to the LPS treatment. B Histogram represents the relative optical intensity of HSP 70 in different treated groups as compared to control. *p < 0.05 represents statistically significant difference between control and LPS + ASH-WEX and LPS + FIV-treated groups. + p < 0.05 represents statistically significant difference between control and LPS-treated group. # p < 0.05 represents statistically significant difference between LPS and LPS + ASH-WEX and LPS + FIV-treated groups

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