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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Aqueous extract from the Withania somnifera leaves as a potential anti-neuroinflammatory agent: a mechanistic study

Fig. 5

ASH-WEX and FIV prevent oxidative stress induced due to neuroinflammation in BV-2 microglial cells. A Represents the confocal images of the (a) CellROX staining, (b) Mitotracker staining, and (c) HSP 70 immunostaining of the LPS-activated BV-2 microglia with or without pretreatment with ASH-WEX and FIV illustrating the decreased levels of the reactive oxygen species and prevention of the mitochondrial turbulences induced due to the LPS treatment. B Representative Western blots of HSP 70, mortalin showing elevated levels of HSP 70, mortalin levels with ASH-WEX and FIV pretreatment. C Histogram presenting mean of densitometric analysis of Western blot signals of HSP 70, mortalin after normalization with α-tubulin

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