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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Aqueous extract from the Withania somnifera leaves as a potential anti-neuroinflammatory agent: a mechanistic study

Fig. 7

ASH-WEX and FIV suppresses proliferation of activated BV-2 microglial cells by causing cell cycle arrest. A iv Represents plots showing the cell cycle analysis of the ASH-WEX- and FIV-treated BV-2 microglia with or without activation with LPS analyzed by PI stain using flow cytometer, and histogram presents the distribution of cells in G0/G1, S, and G2/M phases of cell cycle. B i Representative Western blot of Cyclin D1 and PCNA showing decrease in expression of Cyclin D1 and PCNA on ASH-WEX and FIV treatment. B ii, iii Histograms presenting mean of densitometric analysis of Western blot signals of Cyclin D1 and PCNA after normalization with α-tubulin. The data were obtained from three independent experiments

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