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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Aqueous extract from the Withania somnifera leaves as a potential anti-neuroinflammatory agent: a mechanistic study

Fig. 8

ASH-WEX and FIV induce the apoptosis of the LPS-activated BV-2 microglia. A, ivii Represents the Annexin-FITC assay of the ASH-WEX- and FIV-treated BV-2 microglia with or without activation with LPS using flow cytometer. B i Representative Western blots of Bcl-xl and PARP showing decrease in expression of Bcl-xl and corresponding increase in the level of PARP release on ASH-WEX and FIV treatment. B, ii, iii Histograms presenting mean of densitometric analysis of Western blot signals of Bcl-xl and PARP after normalization with α-tubulin. The data were obtained from three independent experiments. + p < 0.05 represents statistically significant difference between control and LPS-treated group. # p < 0.05 represents statistically significant difference between LPS and LPS + ASH-WEX and LPS + FIV-treated groups

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