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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Cuprizone demyelination induces a unique inflammatory response in the subventricular zone

Fig. 1

MBP levels decrease in the CC after cuprizone treatment and effects of Gal-3 on CC1+ oligodendrocytes. a Representative images of MBP immunohistochemistry in controls and after demyelination of Gal-3 +/+ mice. Scale bar 100 μm. b Graph showing percentage of pixels above the MBP threshold of 150. Statistics calculated as two-way ANOVA with N = 6. Graphs show mean ± SEM. **p < 0.01, ***p < 0.001. c Immunohistochemistry showing co-localization of CC1 and Olig2. White arrows: CC1+/Olig2+. Yellow arrows: CC1-/Olig2+. Scale bar 50 μm. d Percent of Olig2+ cells that are CC1+. Statistics were calculated as two-way ANOVA with N ≥ 6. Graphs show mean ± SEM. **p ≤ 0.01

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