Fig. 3
From: Cuprizone demyelination induces a unique inflammatory response in the subventricular zone
The number of CD45+ cells decreases in the SVZ after cuprizone treatment. a Representative images of CD45 and Iba1 immunohistochemistry in the CC. Scale bar 100 μm. b, c Graphs demonstrating the density of CD45+ cells in the SVZ and CC. d, e Graphs demonstrating the proportion of CD45+ cells that are Iba1+ in the SVZ and CC. Statistics calculated as two-way ANOVA with N < 5. Graphs show mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001. f Representative image of Olig2+ immunohistochemistry from the CC of a WT remyelination mouse. g, h Graphs showing number of Olig2+ cells in the SVZ (g) and density in the CC (h). Statistics calculated using repeated-measures ANOVA for SVZ and two-way ANOVA for CC with N = 6 for each group. Graphs show mean ± SEM. *p < 0.05, ***p < 0.001