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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model

Fig. 4

Histopathological analysis of Streptococcus pneumoniae-infected zebrafish embryos via the hindbrain ventricle at 2 days post fertilization. a, b Sagittal section of the head region showing bacteria (arrow heads) in a the subarachnoid space and b brain parenchyma at 12 h post injection (hpi). c, d Sagittal section at 24 hpi showing increased amount of bacteria in the subarachnoid space (arrow heads) and disruption of the ventricular lining with bacterial infiltration (arrow) in c and a neutrophil (dotted circle) and a phagocytosing macrophage (circle) in d. Scale bars, 10 μm

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