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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: CCR5 ameliorates Japanese encephalitis via dictating the equilibrium of regulatory CD4+Foxp3+ T and IL-17+CD4+ Th17 cells

Fig. 3

The dynamic expression of cytokines and chemokines in CCR5-ablated mice, depending on JE progression. a Expression of pro- and anti-inflammatory cytokines in the CNS. b The expression of CC and CXC chemokines in the CNS. The expression of cytokines and chemokines in the CNS was determined by real-time qRT-PCR at the indicated time points after Ccr5+/+ and Ccr5−/− mice were inoculated i.p. with JEV (3.0 × 107 pfu). Data are averages ± SD of β-actin-normalized cytokine expression derived from at least three independent experiments (n = 4–5). *p < 0.05; **p < 0.01 compared with the levels of the indicated groups

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