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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: The glucagon-like peptide-1 receptor agonist exendin-4 ameliorates warfarin-associated hemorrhagic transformation after cerebral ischemia

Fig. 5

Ex-4 alleviated warfarin-associated HT after cerebral ischemia through PI3K/Akt/GSK-3β pathway. Effects of GSK-3β siRNA and wortmannin on a brain hemoglobin level and b Evans blue extravasation were evaluated 72 h after MCAO. c, d The expression levels of p-β-catenin/β-catenin were also been detected by western blotting. Data are presented as mean ± SD from six independent experiments and analyzed by one-way ANOVA. *P < 0.05 vs. MCAO group; # P < 0.05 vs. MCAO + warfarin group; **P < 0.05 vs. MCAO + warfarin + Ex-4 group

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Journal of Neuroinflammation

ISSN: 1742-2094