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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: The glucagon-like peptide-1 receptor agonist exendin-4 ameliorates warfarin-associated hemorrhagic transformation after cerebral ischemia

Fig. 7

Ex-4 suppressed oxidative DNA damage and lipid peroxidation in warfarin-associated HT after cerebral ischemia. Mice were intravenously treated with either Ex-4 (Ex-4, 10 mg/kg) or Ex-4 plus wortmannin (15 μL/kg) right after reperfusion. The expression levels of a HHE and b 8-OHdG in the brain tissue were detected. Data are presented as mean ± SD from six independent experiments and analyzed by one-way ANOVA. *P < 0.05 vs. MCAO group; # P < 0.05 vs. MCAO + warfarin group; **P < 0.05 vs. MCAO + warfarin + Ex-4 group

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Journal of Neuroinflammation

ISSN: 1742-2094