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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer’s disease

Fig. 2

Soluble thrombomodulin activity (TMa) and expression (TM-Ag) in AD, MCI, and control subject sera. TMa and TM-Ag were assayed by kits as described in the “Methods” section. Top panel represents the combined TMa in MCI and AD patients above age-matched controls. Middle panel shows the differences in TMa between MCI and AD patients. Bottom panel represents the serum levels of TM-Ag in control, MCI, and AD subjects. Data were expressed as mean ± SEM and *p < 0.05

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Journal of Neuroinflammation

ISSN: 1742-2094