Fig. 7
Chronic social defeat increases the number of CD68hi cells. a CD68 staining was used as a proxy for phagocytic activity. Gating strategy used to examine single live cells for the co-expression of CD11b and CD68. Representative bivariate dot plots demonstrate expression of CD68hi on brain cells from all groups, and enhanced expression on cells from chronic SD mice. b The percentage of phagocytic microglia (CD11bhi CD68hi) is significantly elevated in chronic SD mice compared to all other conditions (p < 0.001). Results are expressed as mean ± SEM (n = 8 per group)