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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages

Fig. 9

Acute stress substantially increases number of microglia in numerous brain regions of Cx3cr1 wt/gfp mice. Confocal images showing endogenous GFP expression in the medial prefrontal cortex (top) and dorsal hippocampus (bottom) of Cx3cr1 wt/gfp mice exposed to HC, acute SD, or chronic SD. Insets show magnified view of prelimbic cortex detailing the endogenous expression of GFP in microglia. Tissue was counterstained with DAPI, shown in blue. CG cingulate gyrus, PL prelimbic cortex, IL infralimbic cortex, fmi anterior forceps of the corpus callosum. Scale bars = 100 μm for top and bottom images and 20 μm for inset. A summary of group differences is provided in Table 2; n = 8 per group

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Journal of Neuroinflammation

ISSN: 1742-2094