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Table 1 F values obtained from ANOVA of each microglial morphometric parameter in each brain area

From: Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages

Brain area

# of cells

Morphometric parameter

ANOVA F (3,32), p

  

Cell area

Soma area

Cell spread

Eccentricity

Perimeter

Roundness

PFC

2909

 

19.65, p < 0.0001

   

2.75, p < 0.05

HIPP

2226

 

11.37, p < 0.0001

  

3.14, p < 0.05

18.22, p < 0.0001

PVN

1581

4.15, p < 0.01

14.68, p < 0.0001

3.97, p < 0.02

6.32, p < 0.001

4.17, p < 0.01

3.67, p < 0.05

  1. One-way ANOVA examined the effects of acute or chronic social defeat exposure, or LPS on microglia morphology in three brain regions. Only statistically significant effects and interactions are included. Nonsignificant analyses have been left blank
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Journal of Neuroinflammation

ISSN: 1742-2094