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Table 2 Acute stress exposure elevated the number of microglia in numerous brain regions

From: Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages

Area HC Acute SD Chronic SD ANOVA F (2,23)
IL 68.75 ± 3.38 87.33 ± 4.2a 59.14 ± 1.91 16.71, p < 0.001
PL 105.5 ± 3.47 123.66 ± 3.24a 99 ± 4.94 9.28, p < 0.001
CG 148.72 ± 6.36 193.83 ± 6.83a 126.5 ± 4.54 29.11, p < 0.001
PIR 75.43 ± 6.19 94.5 ± 2.67a 74.75 ± 4.26 5.26, p < 0.02
Acb 153.97 ± 2.62 173.96 ± 6.47b 128.43 ± 12.44 6.83, p < 0.01
dBST 49.29 ± 1.94 45.66 ± 3.71 47.75 ± 2.98  
vBST 60.57 ± 6.29 63.33 ± 2.15 67.87 ± 4.47  
PVN 104.5 ± 8.92 109.28 ± 6.55 117.37 ± 11.34  
Dorsal DG 214.3 ± 10.17 275.4 ± 6.6a 219.42 ± 11.54 11.1, p < 0.001
BLA 96.43 ± 5.17 148.75 ± 5.28a 115 ± 4.85 24.12, p < 0.001
DR 88.75 ± 7.82 95.2 ± 3.17 87.4 ± 5.03  
PAG 194.33 ± 9.2 181.6 ± 3.14 167 ± 11.4  
  1. The number of microglia in examined brain regions of CX3CR1GFP/+ mice housed either in homecage (HC) or exposed to social defeat for 3 days (acute SD) or 14 days (chronic SD). Values are expressed as mean ± SEM (n = 8 per group). Means with (a) indicate significant difference versus all other groups (p < 0.01). Means with (b) indicate significance versus chronic SD samples (p < 0.01). F values obtained from one-way ANOVAs for microglia number in each brain region