Fig. 1
From: Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice
Neuronal fractalkine was downregulated following AOM administration. a Fractalkine mRNA expression in the cortex during the timecourse of AOM-induced HE with appropriate time-matched tissue analyses from vehicle-treated controls. b Fractalkine concentrations in cortex lysate normalized to protein concentrations of cortex lysates from vehicle and AOM-treated timecourse mice. c Immunofluorescence for fractalkine (green) and NeuN (red) with DAPI (blue) used as a nuclear counterstain in vehicle cortex brain tissue. d Fractalkine mRNA expression in neurons isolated from vehicle-treated and AOM-treated mice cortices. For mRNA expression and fractalkine ELISA analyses, *p < 0.05 compared to vehicle-treated mice or neurons from vehicle-treated mice, **p < 0.01 compared to vehicle-treated mice. n = 3 for fractalkine mRNA and ELISA analyses