Skip to main content

Table 1 Comparison of characteristics of WDR neurones in carrageenan versus saline-treated rats

From: Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models

 

Saline-treated (n = 15)

Carrageenan-treated (n = 38)

% Change vs saline-treated

Depth (μm)

677 ± 31

747 ± 21

NA

Threshold (mA)

 Aβ

0.14 ± 0.01

0.19 ± 0.01##

130

 C

1.47 ± 0.08

1.81 ± 0.10*

124

Latency (ms)

 Aβ

7.6 ± 0.79

7.3 ± 0.40

96

 C

182.3 ± 8.76

191.0 ± 8.50

105

Electrically evoked responses (number of APs)

 Aβa

121 ± 10

126 ± 8

104

 Aβb

143 ± 10

145 ± 8

101

 Aδb

91 ± 16

148 ± 17##

163

 Cb

431 ± 49

497 ± 41

114

 PDb

352 ± 49

381 ± 37

106

 Inputb

271 ± 51

368 ± 60

136

 WUb

505 ± 60

502 ± 46

100

  1. Characteristics of spinal WDR neurones recorded at approximately 30 h following intraplantar injection of 2 % λ-carrageenan or saline
  2. *p < 0.05 unpaired t test, ## p < 0.01 Mann-Whitney U test
  3. APs action potentials, NA not applicable
  4. aResponses electrically evoked by 3× Aβ-fibre threshold
  5. bResponses electrically evoked by 3× C-fibre threshold