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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Secreted herpes simplex virus-2 glycoprotein G alters thermal pain sensitivity by modifying NGF effects on TRPV1

Fig. 2

SgG2 increases NGF-dependent TRPV1 serine phosphorylation. DRG neurons were grown for 3 days in NGF medium, NGF starved for 16 h, and stimulated with HEPES, NGF in HEPES, or NGF plus SgG2 for 30 min. Western blots showing phosphorylation of TrkA and p38 (a) and TRPV1 phosphorylation in serine residues (b), which was detected following TRPV1 immunoprecipitation. c Graph showing the quantified serine phosphorylation in TRPV1. The data corresponds to the average of three independent experiments for TRPV1 serine phosphorylation. Error bars represent the mean plus standard deviation *p < 0.05

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Journal of Neuroinflammation

ISSN: 1742-2094