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Table 1 Baseline characteristics of patients according to the presence/absence of PH or sICH

From: Dynamic change of neutrophil to lymphocyte ratio and hemorrhagic transformation after thrombolysis in stroke

 

No PH (n = 161)

PH (n = 28)

P

No sICH (n = 172)

sICH (n = 17)

P

Age, years, mean (SD)

64.1 ± 10.3

70.1 ± 10.5

0.005

64.6 ± 10.4

68.7 ± 11.7

0.133

Females, %

59 (36.6)

7 (25.0)

0.233

60 (34.9)

6 (35.3)

0.973

Body mass index, kg/m2, mean (SD)

24.4 ± 3.1

23.9 ± 3.0

0.401

24.4 ± 3.0

24.0 ± 3.5

0.601

Hypertension, %

101 (62.7)

21 (75.0)

0.210

111 (64.5)

11 (64.7)

0.989

Diabetes, %

50 (31.1)

7 (25.0)

0.519

51 (29.7)

6 (35.3)

0.629

Hyperlipidemia, %

73 (45.3)

12 (42.9)

0.807

79 (45.9)

6 (35.3)

0.400

Previous stroke, %

14 (8.7)

5 (17.9)

0.251

17 (9.9)

2 (11.8)

1.000

Coronary artery disease, %

18 (11.2)

5 (17.9)

0.494

19 (11.0)

4 (23.5)

0.266

Atrial fibrillation, %

48 (29.8)

12 (42.9)

0.171

50 (29.1)

10 (58.8)

0.012

Current smokers, %

53 (32.9)

8 (28.6)

0.650

56 (32.6)

5 (29.4)

0.791

Ongoing antiplatelet therapy, %

9 (5.6)

7 (25.0)

0.002

12 (7.0)

4 (23.5)

0.060

SBP, mm Hg, mean (SD)

148.4 ± 18.4

154.5 ± 17.1

0.104

148.9 ± 18.2

153.2 ± 18.7

0.302

DBP, mm Hg, mean (SD)

81.4 ± 9.8

83.2 ± 10.4

0.368

81.3 ± 9.7

84.8 ± 11.2

0.163

Blood glucose, mmol/L, median (IQR)

7.2 (5.3–9.0)

7.0 (5.8–9.5)

0.133

7.0 (5.3–9.0)

8.0 (5.5–9.5)

0.645

Platelets, 109/L, mean (SD)

187.9 ± 50.8

178.9 ± 40.0

0.371

187.3 ± 49.9

179.7 ± 44.5

0.545

INR, mean (SD)

1.01 ± 0.08

1.01 ± 0.09

0.468

1.01 ± 0.08

1.03 ± 0.08

0.302

Baseline NIHSS, median (IQR)

11 (6–15)

17 (10–22.5)

0.001

12 (6–15)

13 (10–20)

0.198

Onset to treatment, min, mean (SD)

170.6 ± 48.8

183.4 ± 51.9

0.207

171.1 ± 48.9

187.2 ± 52.1

0.198

IV rtPA + endovascular therapy, %

49 (30.4)

9 (32.1)

0.856

51 (29.7)

7 (41.2)

0.326

  1. DBP diastolic blood pressure, INR international normalized ratio, IQR interquartile range, IV rtPA intravenous recombinant tissue plasminogen activator, NIHSS National Institutes of Health Stroke Scale, PH parenchymal hemorrhage, SBP systolic blood pressure, SD standard deviation, sICH symptomatic intracranial hemorrhage