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Table 1 Baseline characteristics of patients according to the presence/absence of PH or sICH

From: Dynamic change of neutrophil to lymphocyte ratio and hemorrhagic transformation after thrombolysis in stroke

  No PH (n = 161) PH (n = 28) P No sICH (n = 172) sICH (n = 17) P
Age, years, mean (SD) 64.1 ± 10.3 70.1 ± 10.5 0.005 64.6 ± 10.4 68.7 ± 11.7 0.133
Females, % 59 (36.6) 7 (25.0) 0.233 60 (34.9) 6 (35.3) 0.973
Body mass index, kg/m2, mean (SD) 24.4 ± 3.1 23.9 ± 3.0 0.401 24.4 ± 3.0 24.0 ± 3.5 0.601
Hypertension, % 101 (62.7) 21 (75.0) 0.210 111 (64.5) 11 (64.7) 0.989
Diabetes, % 50 (31.1) 7 (25.0) 0.519 51 (29.7) 6 (35.3) 0.629
Hyperlipidemia, % 73 (45.3) 12 (42.9) 0.807 79 (45.9) 6 (35.3) 0.400
Previous stroke, % 14 (8.7) 5 (17.9) 0.251 17 (9.9) 2 (11.8) 1.000
Coronary artery disease, % 18 (11.2) 5 (17.9) 0.494 19 (11.0) 4 (23.5) 0.266
Atrial fibrillation, % 48 (29.8) 12 (42.9) 0.171 50 (29.1) 10 (58.8) 0.012
Current smokers, % 53 (32.9) 8 (28.6) 0.650 56 (32.6) 5 (29.4) 0.791
Ongoing antiplatelet therapy, % 9 (5.6) 7 (25.0) 0.002 12 (7.0) 4 (23.5) 0.060
SBP, mm Hg, mean (SD) 148.4 ± 18.4 154.5 ± 17.1 0.104 148.9 ± 18.2 153.2 ± 18.7 0.302
DBP, mm Hg, mean (SD) 81.4 ± 9.8 83.2 ± 10.4 0.368 81.3 ± 9.7 84.8 ± 11.2 0.163
Blood glucose, mmol/L, median (IQR) 7.2 (5.3–9.0) 7.0 (5.8–9.5) 0.133 7.0 (5.3–9.0) 8.0 (5.5–9.5) 0.645
Platelets, 109/L, mean (SD) 187.9 ± 50.8 178.9 ± 40.0 0.371 187.3 ± 49.9 179.7 ± 44.5 0.545
INR, mean (SD) 1.01 ± 0.08 1.01 ± 0.09 0.468 1.01 ± 0.08 1.03 ± 0.08 0.302
Baseline NIHSS, median (IQR) 11 (6–15) 17 (10–22.5) 0.001 12 (6–15) 13 (10–20) 0.198
Onset to treatment, min, mean (SD) 170.6 ± 48.8 183.4 ± 51.9 0.207 171.1 ± 48.9 187.2 ± 52.1 0.198
IV rtPA + endovascular therapy, % 49 (30.4) 9 (32.1) 0.856 51 (29.7) 7 (41.2) 0.326
  1. DBP diastolic blood pressure, INR international normalized ratio, IQR interquartile range, IV rtPA intravenous recombinant tissue plasminogen activator, NIHSS National Institutes of Health Stroke Scale, PH parenchymal hemorrhage, SBP systolic blood pressure, SD standard deviation, sICH symptomatic intracranial hemorrhage