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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1

Fig. 5

C3 immunohistochemistry in WT, MASP-2−/−, and MASP-1/3−/− mice. Representative micrographs of C3 deposition in the ischemic cortices of WT (a), MASP-2−/− (b), and MASP-1/3−/− (c) mice 48 h after tMCAO (scale bar = 20 μm). The quantification of C3 staining shows that MASP-2−/− mice had reduced C3 deposition when compared to WT while MASP-1/3−/− were not different (d). Data are reported as scatter-dot plots and mean bars. *P < 0.05; **P < 0.01, one-way ANOVA followed by Tukey’s post hoc test

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