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Table 3 Inflammatory load score (ILS) of each group of rats (sham-vehicle, sham-EFX, TBI-vehicle, TBI-EFX, n = 5/groups) measured in the ipsilateral side of the lesion 6 hours post TBI

From: Etifoxine improves sensorimotor deficits and reduces glial activation, neuronal degeneration, and neuroinflammation in a rat model of traumatic brain injury

 

Sham

TBI

Vehicle

EFX

p value

Vehicle

EFX

p value

Mean ILS (SEM)

2.371 (0.21)

2.114 (0.15)

0.292

3.371 (0.15)

2.464 (0.16)

0.003

  1. Ipsilateral cortices were analyzed with the Bio-Plex Pro™ rat cytokine assays. The cytokines used for the score were IL-1α, IL-1β, IL-2, IL-6, IL-12, TNF-α, and GM-CSF. Data represents mean (SEM)