TY - JOUR AU - Okazaki, Rentaro AU - Doi, Toru AU - Hayakawa, Kentaro AU - Morioka, Kazuhito AU - Imamura, Osamu AU - Takishima, Kunio AU - Hamanoue, Makoto AU - Sawada, Yasuhiro AU - Nagao, Motoshi AU - Tanaka, Sakae AU - Ogata, Toru PY - 2016 DA - 2016/09/05 TI - The crucial role of Erk2 in demyelinating inflammation in the central nervous system JO - Journal of Neuroinflammation SP - 235 VL - 13 IS - 1 AB - Brain inflammation is a crucial component of demyelinating diseases such as multiple sclerosis. Although the initiation of inflammatory processes by the production of cytokines and chemokines by immune cells is well characterized, the processes of inflammatory aggravation of demyelinating diseases remain obscure. Here, we examined the contribution of Erk2, one of the isoforms of the extracellular signal-regulated kinase, to demyelinating inflammation. SN - 1742-2094 UR - https://doi.org/10.1186/s12974-016-0690-8 DO - 10.1186/s12974-016-0690-8 ID - Okazaki2016 ER -