Fig. 6
From: The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-β peptide
ANXA1 reduces the Aβ-induced expression of pro-inflammatory mediators in microglia. Quantification of mRNA levels of inflammatory mediators in BV2 cells treated with 3 μM Aβ1–42 with or without 5 μg/ml hrANXA1 for 16 h. a Il6 (n = 6–12 samples). b Tnf (n = 6–17). c Il4 (n = 6–9 samples). d Arg1 (n = 6–9 samples). e Il10 (n = 6–14 samples). f Tgfb1 (n = 6 samples). Values shown in graphs represent the mean value ± SEM and are expressed as fold change in comparison to the normalized control. Statistical analysis included one-way ANOVA with Bonferroni’s multiple-comparison post-test or Kruskal-Wallis test with Dunn’s multiple-comparison post-test, *p < 0.05, **p < 0.01