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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: A murine model of inflammation-induced cerebral microbleeds

Fig. 1

Significant development of surface microhemorrhages in mice treated with LPS (n = 10) (3 mg/kg at 0, 6, and 24 h) compared with saline-treated mice (n = 12) and regional differences in the distribution of surface microhemorrhages in LPS-treated mice (a) in the 2-day experiment. Brain images showing absence of surface microhemorrhages in saline-treated mice (b) and presence of surface microhemorrhages in the olfactory bulb (left panel) and the cerebellum (right panel) of LPS-treated mice (c). Significantly higher surface microhemorrhages in mice treated with LPS (n = 9) (1 mg/kg at 0, 6, and 24 h) compared with the saline-treated mice (n = 9) in the 7-day experiment (d). Data are presented as mean ± SEM. Student’s t test for two groups and one-way ANOVA with Bonferroni’s post-test for more than two groups; *p < 0.05, **p < 0.01

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