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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: A murine model of inflammation-induced cerebral microbleeds

Fig. 2

Acute H&E-positive cerebral microhemorrhages: Significant development of acute (H&E-stained) parenchymal microhemorrhages in mice treated with LPS (n = 10) (3 mg/kg, at 0, 6, and 24 h) compared with saline-treated mice (n = 12) (comparisons shown in black) (a). Significant difference in regional distribution of H&E-positive parenchymal microhemorrhages in the LPS-treated group (comparisons shown in blue) (a). Representative images showing H&E-positive cerebral microhemorrhages in the cortex, sub-cortex, and cerebellum of LPS- and saline-treated mice (b). Representative image showing a cerebral blood vessel associated with an acute (H&E-positive) cerebral microhemorrhage (c). Data are presented as mean ± SEM. Two-way repeated measure ANOVA with Bonferroni’s post-test; *p < 0.05, **p<0.01, ****p < 0.0001. Scale bar = 100 μm

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